Cutaneous Hydroxysteroid Dehydrogenases and Rat Hair Cycle

    January 1975 in “ Archives of Dermatological Research ”
    Crovato Franco, Bertamino Rino, Moretti Giuseppe
    From the encyclopedia
    dehydroepiandrosterone →
    Estradiol →

    an estrogen promoting hair regrowth more commonly used in women

    Studysummary Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study investigated the histochemical activity of various hydroxysteroid dehydrogenases during a provoked hair cycle in rat skin. High reaction intensity was observed with dehydroepiandrosterone, estradiol, androsterone, and pregnenolone, while no reaction was noted with 11-beta-hydroxyprogesterone, testosterone, dihydrotestosterone, 17-alpha-hydroxypregnenolone, and 17-alpha-hydroxyprogesterone. The reactivity varied with the hair cycle, and the reactive sites were identified as the acini of sebaceous glands and the hair sheaths.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results