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Did you mean 17-hydroxyprogesterone?

Glossary 17-hydroxyprogesterone

steroid hormone involved in cortisol and sex hormone production

17-hydroxyprogesterone (17-OHP) is a steroid hormone produced in the adrenal glands and gonads as part of the process of synthesizing cortisol and other hormones. Elevated levels of 17-OHP can indicate congenital adrenal hyperplasia (CAH), a genetic disorder affecting hormone production, and it is often measured in newborn screening tests to diagnose this condition early.

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Research

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American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

343 citations , October 2015 in “Endocrine Practice”

This review discusses the diagnostic criteria and management strategies for Polycystic Ovary Syndrome (PCOS) and highlights the need for comprehensive clinical assessment, but does not report new clinical findings.

research Ketoconazole Therapy for Women with Acne and/or Hirsutism

46 citations , August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.

research [Hormonal profile in men with premature androgenic alopecia].

4 citations , January 2000 in “PubMed”

In this study, researchers found that young men with premature androgenetic alopecia had a hormonal profile similar to the pattern seen in women with polycystic ovary syndrome, suggesting a possible genetic link.

research Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle

2 citations , January 1975 in “Archives of Dermatological Research”

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

research Correlation of ovarian volume and clinical and laboratory parameters of PCOS in Korean patients

1 citations , March 2022 in “Clinical and Experimental Obstetrics & Gynecology”

This study found that in Korean women with polycystic ovary syndrome, higher ovarian volumes were significantly associated with increased serum levels of free testosterone, total testosterone, and 17-alpha-hydroxyprogesterone.

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Community Join

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community 17-alpha-estradiol/Alfatradiol how does it Work for Hair loss?

2 upvotes 1 year ago

17-alpha-estradiol may work for hair loss by inhibiting 5-alpha reductase, similar to finasteride. It might lower testosterone in the scalp, reducing DHT conversion.

community Mechanism of action of alfatradiol (17 alpha estradiol)

5 upvotes 2 years ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community DNA test result is incredible !

in Technology 31 upvotes 7 months ago

The conversation discusses a personalized hair loss treatment plan based on DNA test results, recommending Minoxidil, Dutasteride, 17-alpha Estradiol, Cetirizine, and PRP sessions. The test identifies a high risk of hair loss due to DHT but a good response to Minoxidil, suggesting a tailored approach to treatment.

community The first three months on minoxidil 2%

in Is this regrowth? 1 upvotes 1 year ago

The user noticed hair thinning and has been using a treatment with minoxidil 2%, hydrocortisone butyrate, and 17 alpha estradiol for three months, seeing some regrowth. The user had dermatitis, now cured, which worsened the hair loss.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

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Learn

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learn dehydroepiandrosterone

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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