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    Did you mean 3β-Hydroxysteroid Dehydrogenase?
    Glossary 3β-Hydroxysteroid Dehydrogenase

    enzyme crucial for converting steroid precursors into active hormones

    3β-Hydroxysteroid Dehydrogenase (3β-HSD) is an enzyme that plays a crucial role in the biosynthesis of all classes of hormonal steroids, including androgens, estrogens, and glucocorticoids. It catalyzes the conversion of Δ5-3β-hydroxysteroids to Δ4-3-ketosteroids, a key step in the production of hormones that regulate various physiological processes, including hair growth and skin health.

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    Research 10 of 951

    1. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations
    2. Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle Archives of Dermatological Research · 1975 · 2 citations
    3. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    4. Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome Nature Clinical Practice Endocrinology & Metabolism · 2005 · 69 citations
    5. Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands Journal of Investigative Dermatology · 1998 · 45 citations
    6. A Platform for Determining Medicinal Plants with Targeted 17β-Hydroxysteroid Dehydrogenase Modulation for Possible Hair Loss Prevention Cosmetics · 2024
    7. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    8. Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ<sup>5</sup>-Δ<sup>4</sup>-lsomerase in Human Adrenals and Gonads Molecular Endocrinology · 1991 · 354 citations
    9. Localization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in Skin Journal of Investigative Dermatology · 2010 · 119 citations
    10. Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: Studies on the natural history of the defect and effect of androgens on gender role Journal of Steroid Biochemistry · 1983 · 98 citations
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