38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
38 citations,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
37 citations,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
37 citations,
April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
37 citations,
January 1991 in “Reproductive Toxicology” Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
35 citations,
May 2019 in “Frontiers in genetics” Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.
35 citations,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
34 citations,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
34 citations,
December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” Rat vibrissa follicles are useful for studying hair growth cycles, especially the transition from pro-anagen to anagen.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
33 citations,
September 2017 in “Journal of clinical immunology” New treatments for immune disorders caused by FOXN1 deficiency are promising.
33 citations,
June 2017 in “Developmental Biology” Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.
33 citations,
May 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
32 citations,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
32 citations,
May 2015 in “Journal of Investigative Dermatology” Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
32 citations,
January 2003 in “Facial Plastic Surgery” The technique improves facial aging signs with a low risk of complications and a recovery time of about 3 weeks.
32 citations,
December 1969 in “The Lancet” Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
31 citations,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
31 citations,
February 2014 in “Journal of dermatological science” Placental growth factor may help treat hair loss.
31 citations,
June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
31 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
31 citations,
January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
30 citations,
October 2016 in “Current research in translational medicine” Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
30 citations,
July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
30 citations,
May 2010 in “British Journal of Dermatology” Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.
30 citations,
June 2008 in “Dermatologic Surgery” The SAFE System may improve hair transplant results but isn't suitable for everyone.
30 citations,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.