research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
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research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals
Gut microbes significantly affect brain steroid levels.
research Prostate Cancer and Androgenic Alopecia
The document suggests more research is needed to understand the link between baldness and prostate cancer.
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Trace Elements Content and Hormonal Profiles in Women with Androgenetic Alopecia
Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
research Effects of the Anti-Androgen Finasteride on 5-Alpha-Reductase Activity in Human Gingival Fibroblasts in Response to Minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
research Activation of Hair Cell Growth Factors by Linoleic Acid in Malva Verticillata Seed
Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.
research Nutrition and Acne: The Role of Diet in Acne Development
Diet, especially dairy and high-sugar foods, can cause acne.
research Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
research Hormone-Dependent Medial Preoptic, Lumbar Spinal Cord, and Autonomic Coordination Supporting Male Sexual Behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research The Role of Androgen Therapy
Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
research Response to the Letter to the Editor: Androgenetic Alopecia, Drug Safety, and Therapeutic Strategies
Use finasteride over dutasteride for hair loss; consider topical treatments and weigh risks.
research Male Pattern Hair Loss: Current Understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research An Overview of Alopecias
The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
research Understanding Androgenetic Alopecia: Continuing Medical Education
The document concludes that androgenetic alopecia is common, has a genetic link, and can be diagnosed and treated with medications like finasteride and minoxidil.
research Oral and Topical Administration of Standardized Saw Palmetto Oil Reduces Hair Fall and Improves Hair Growth in Androgenetic Alopecia Subjects: A 16-Week Randomized, Placebo-Controlled Study
Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.
research Post-Finasteride Syndrome: Real or Myth?
Post-finasteride syndrome is rare but serious and should be taken seriously.
research Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Nourkrin: Objective and Subjective Effects and Tolerability in Persons with Hair Loss
Nourkrin® significantly increased hair growth and was well-tolerated by people with hair loss.
research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
research Treatment of Hirsutism with Flutamide and a Low-Dosage Oral Contraceptive in Polycystic Ovarian Disease Patients
Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
research Effect of Finasteride on Adrenal Steroidogenesis in Men
Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research Characterization of Response of Murine Hair Follicle-Derived Keratinocytes Against Androgen and Testosterone 5α-Reductase Activity
Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.
research Synergistic Therapeutic Effect of Ginsenoside Rg3 Modified Minoxidil Transfersomes on Androgenic Alopecia in C57BL/6 Mice
Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.
research Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men
Testosterone improves mood and thinking skills; finasteride has no effect.
research The Development of BRL 7660 as an Anti-Acne Agent
BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.