Post-Finasteride Syndrome: Real or Myth?

June 2024 in “ Trends in Urology & Men s Health ”

Culley C. Carson

post-finasteride syndrome finasteride sexual side effects neurological side effects psychological side effects Propecia

TLDR Post-finasteride syndrome is rare but serious and should be taken seriously.

Post-finasteride syndrome (PFS) is characterized by persistent sexual, neurological, and psychological side effects in men after they stop taking finasteride. While PFS is uncommon, it poses significant challenges for those affected. Despite being a controversial condition with no proven treatments, the syndrome warrants attention and should not be dismissed.

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Research cited in this study

14 / 14 results

research Analysis of Finasteride Treatment and Its Withdrawal in Rat Hypothalamus and Hippocampus at Whole-Transcriptome Level

March 2024 in “Journal of Endocrinological Investigation”

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

research The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms

3 citations, September 2023 in “International journal of impotence research”

Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.

research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal

1 citations, August 2023 in “Andrology”

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

research US Food and Drug Administration Warning Regarding Finasteride and Suicidal Ideation: What Should Urologists Know?

April 2023 in “European urology open science”

Urologists should screen for mental health issues before and during finasteride treatment.

research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases

2 citations, May 2022 in “International Journal of Impotence Research”

Finasteride may be linked to Peyronie’s disease, but more research is needed.

research Diagnostic Criteria for Enduring Sexual Dysfunction After Treatment With Antidepressants, Finasteride, and Isotretinoin

8 citations, October 2021 in “The international journal of risk and safety in medicine”

The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.

The Connection of 5-Alpha Reductase Inhibitors to the Development of Depression

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research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia

38 citations, June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.

research Advances in the Treatment of Male Androgenetic Alopecia: A Brief Review of Finasteride Studies

10 citations, June 2001 in “PubMed”

Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.

Post-Finasteride Syndrome: Real or Myth?

Research cited in this study

research Analysis of Finasteride Treatment and Its Withdrawal in Rat Hypothalamus and Hippocampus at Whole-Transcriptome Level

research The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms

research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal

research US Food and Drug Administration Warning Regarding Finasteride and Suicidal Ideation: What Should Urologists Know?

research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases

research Diagnostic Criteria for Enduring Sexual Dysfunction After Treatment With Antidepressants, Finasteride, and Isotretinoin

research The Connection of 5-Alpha Reductase Inhibitors to the Development of Depression

research Differential Gene Expression in Post-Finasteride Syndrome Patients

research Suicidality and Psychological Adverse Events in Patients Treated with Finasteride

research Post-Finasteride Syndrome: A Surmountable Challenge for Clinicians

research Post-Finasteride Syndrome: An Emerging Clinical Problem

research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride

research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss

research Finasteride 5mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon?

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research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia

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