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A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Eclipta alba extract may help treat obesity by blocking fat cell formation and lowering blood lipid levels.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

The document concludes that there are multiple ways to create PCOS in animals for research, which helps understand and treat the condition.

SCD1 is crucial for skin health and overall energy balance.

Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.