1 citations
,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
27 citations
,
October 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
165 citations
,
July 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
66 citations
,
July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
112 citations
,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
51 citations
,
June 2014 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
38 citations
,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
22 citations
,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
39 citations
,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
82 citations
,
July 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
173 citations
,
September 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
1 citations
,
September 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
July 2021 in “IntechOpen eBooks” Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.
15 citations
,
August 2017 in “International Journal of Molecular Medicine” Panax ginseng extract may help prevent hair loss caused by DKK-1.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
14 citations
,
July 2019 in “Experimental and Molecular Medicine” Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.
1 citations
,
December 2023 in “Animals” Winter provides the best fur quality for Rex rabbits due to seasonal changes in specific signaling pathways.
4 citations
,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
May 2022 in “Frontiers in Cell and Developmental Biology” miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
30 citations
,
January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
8 citations
,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
January 2020 in “Elsevier eBooks” Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
207 citations
,
April 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
8 citations
,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
1 citations
,
May 2023 in “Frontiers in Pharmacology” Millet seed oil may help hair grow by activating certain cell growth signals.
60 citations
,
January 2012 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.