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Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Sex hormones, especially androgens, play a key role in causing acne.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

New genes and pathways are important for testosterone production and male sexual development.

Finasteride doesn't affect bone density in male rats.

Suppressing certain hormones might help prevent prostate cancer.

Sex hormones affect brain cells differently in males and females.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Finasteride doesn't affect bone density in male rats.