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An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Aromatase inhibitors cause male pattern hair loss in women.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

The document explains how male reproductive hormones work and affect the body.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Male hormones worsen kidney transplant damage, but blocking them helps.

Men with thinner hair from genetic hair loss may be more likely to have an enlarged prostate.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Compound 4 is a promising treatment for hair loss with low toxicity.

Lespedeza cuneata extract may help treat enlarged prostate.

Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.

The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.