Search

everythinglearnresearchcommunity

for

Search:↓

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Mice with human gene experienced hair loss when treated with DHT.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Clascoterone may be an effective topical treatment for hair loss.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

New compounds were made that are promising for prostate cancer therapy.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.

Certain gene variations are significantly linked to hair loss, especially in white people.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Finasteride helps reduce heart issues and improves heart function.