Faculty Opinions Recommendation of Androgen Receptor Gene Polymorphisms and Risk for Androgenetic Alopecia: A Meta-Analysis

    October 2011 in “ Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ”
    Abraham Zlotogorski, Yuval Ramot
    Image of study
    TLDR Certain gene variations are significantly linked to hair loss, especially in white people.
    This document is a meta-analysis that examines the association between androgen receptor (AR) gene polymorphisms and the risk for androgenetic alopecia (AGA). AGA is a type of hair loss that is dependent on testosterone, dihydrotestosterone, and a functional AR. The researchers analyzed eight studies and found that only the StuI polymorphism in the AR gene showed a significant association with AGA, particularly in the white population. The authors suggest that further studies are needed to better understand the complex genetic basis of AGA.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Maintaining hair until Breezula without Fin

      in Treatment  6 upvotes 4 years ago
      A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

      community Binding affinity of pyrilutamide!

      in Update  167 upvotes 2 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Hair loss causes are still a myth.

      in Chat  16 upvotes 3 years ago
      The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  122 upvotes 1 year ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

    Similar Research

    5 / 1000+ results