G-Proteins, Receptor Signal Transduction, and Growth Hormone Secretion

    March 1993 in “ PubMed
    C. Ventra, Alfonso junior Apicella, Gennaro Schettini, B Merola, Gaetano Lombardi
    From the encyclopedia
    Cyproterone →

    a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Studysummary This review discusses the clinical forms and causes of androgenization in women, as well as therapeutic options, reporting success with antiandrogens like cyproterone acetate and spironolactone for skin symptoms, though results are not permanent.
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