This review discusses the clinical forms and causes of androgenization in women, as well as therapeutic options, reporting success with antiandrogens like cyproterone acetate and spironolactone for skin symptoms, though results are not permanent.
151 citations
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December 2004 in “Annals of the New York Academy of Sciences” This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
3 citations
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November 2005 in “Women's health” This narrative review discusses various causes and treatments of hirsutism in women, emphasizing the importance of identifying androgen-secreting tumors, but does not present new study results.
26 citations
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March 2009 in “Dermato-endocrinology” This review discusses the evaluation, clinical presentation, and cutaneous manifestations of congenital adrenal hyperplasia, focusing on differential diagnosis challenges with polycystic ovary syndrome, and reports no new clinical findings.
70 citations
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April 2014 in “Annales d'endocrinologie” This review discusses the pathways of androgen biosynthesis and reports no new findings, highlighting the need to understand the interplay between the classic and backdoor pathways.