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The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Finasteride and dutasteride do not significantly change beard thickness in men.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Apigenin may help promote hair growth and could treat hair loss.

Thyroid problems can cause hair loss and change hair texture.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.

Sex hormones affect brain cells differently in males and females.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

The endocannabinoid system affects oil production and inflammation in skin cells.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Changes in skin bacteria can affect hair loss and new treatments targeting these bacteria may prevent balding without sexual side effects.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.