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Testosterone increases muscle mass regardless of DHT conversion blocking.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Testosterone's muscle-building effects do not require its conversion to DHT.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

New compounds may soon be tested to treat excessive hair growth in women.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Testosterone helps human pancreatic cells increase insulin release.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.