March 2021 in “CRC Press eBooks” This review discusses the cosmetic applications and healing phases of microneedling and reports no new clinical findings; the authors highlight its use for skin and hair treatments without epidermal damage.
This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.
In this case study, a 65-year-old male with androgenetic alopecia showed slight hair growth after treatment with a Derma Roller System and Capillary Therapy.
17 citations
,
September 2022 in “Biomaterials Research” This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.
328 citations
,
November 2020 in “Nature Materials” This study found that D-peptide crosslinked MAP hydrogel accelerated material degradation in vivo but significantly enhanced skin regeneration, suggesting an adaptive immune response can drive regenerative healing even with rapid scaffold breakdown.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.
24 citations
,
November 2021 in “PLoS ONE” In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.
8 citations
,
July 2008 in “Facial Plastic Surgery Clinics of North America” This overview highlights an increase in nonsurgical cosmetic procedures and a growing number of male patients seeking cosmetic treatments, without reporting new clinical results.
4 citations
,
August 2007 in “Journal of The American Academy of Dermatology” This article discusses various aspects of rhinophyma, including its pathogenesis, differential diagnosis, and treatment options, without presenting new clinical research results.
July 2023 in “Clinical, cosmetic and investigational dermatology” In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.
131 citations
,
May 2015 in “Experimental Dermatology” This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that a newly developed hemi-vascularized sandwich method significantly improved the regeneration and maturity of hair follicles compared to other transplantation approaches in rat models.
May 2023 in “Elsevier eBooks” This article discusses scalp micropigmentation as a noninvasive method to conceal various forms of hair loss and scalp abnormalities and reports no clinical results; the authors highlight its safe and effective application.
August 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract discusses the non-invasive technique of scalp micropigmentation for hair loss, focusing on its cosmetic effects and customization options, and reports no new research findings.
January 2021 in “Journal of Cutaneous and Aesthetic Surgery” Platelet-rich plasma with microneedling is effective for hair loss, but the number of sessions needed varies.
January 2020 in “한국공업화학회 연구논문 초록집” This study found that microencapsulated dermal papilla cells in hyaluronic acid/collagen hydrogel retained their ability to initiate hair follicle regeneration, suggesting potential for alopecia treatment.
4 citations
,
July 2021 in “Journal of dermatology & dermatologic surgery” This review discusses the use of microneedling with a dermaroller for treating acne scars, hair loss, and wrinkles, and reports no new clinical results.
6 citations
,
July 2017 in “Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses” This abstract does not provide research results or a summary of findings, but only lists author affiliations and contact information.
February 2020 in “International Journal of Contemporary Medicine” In this study, 46 patients aged 18-25 with atrophic acne scars underwent microneedling combined with autologous platelet-rich plasma therapy, resulting in significant improvement in 86.9% of cases without serious complications, suggesting this combination is effective for enhancing the appearance of acne scars.
19 citations
,
October 2020 in “Biomedical Microdevices” This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.
1 citations
,
February 2004 in “Dermatologic Surgery” This study found that using deep plane fixation during scalp surgeries significantly reduced closure tension and allowed for increased tissue excision compared to standard techniques without fixation.
February 2004 in “Dermatologic Surgery” This study found that deep plane fixation in scalp surgeries allowed for tension-reduced wound closures and increased tissue excision compared to techniques without deep plane fixation.
3 citations
,
October 2019 in “Pharmaceutics” This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
May 2026 in “Journal of Nanobiotechnology” This study found that using a palmitoylated peptide, Pal-MPAPO, delivered through hydrogel microneedles effectively promoted hair regrowth in mice with efficacy comparable to minoxidil, while requiring less frequent application.
36 citations
,
August 2017 in “Journal of Cosmetic Dermatology” In this study, patients with mild to moderate androgenetic alopecia who received platelet-rich plasma injections with microneedling showed improvements in hair growth and thickness, as well as high satisfaction, over a three-month period compared to conventional therapy non-responders.
24 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses scalp micropigmentation techniques and their customization to individual patients, but reports no new clinical results.
10 citations
,
March 2015 in “PubMed” This paper demonstrates that scalp micropigmentation can effectively conceal scalp and hair deformities with high patient satisfaction, offering a non-surgical alternative cosmetic solution.