Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report

    Sihao Shen, Jianfeng Feng, Xiuzu Song, Wenzhong Xiang
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    TLDR Reflectance confocal microscopy helped tell periorificial dermatitis apart from similar skin conditions.
    Reflectance confocal microscopy (RCM) was utilized to assist in the diagnosis of periorificial dermatitis (PD), an inflammatory facial skin disorder. The RCM images revealed slight edema in the spinous layer, numerous dendritic cells, keratotic plugging and dilation of hair follicles, as well as dilation and congestion of blood vessels in the superficial dermis. Additionally, there was an observed increase in vascular density, accelerated blood flow, and a higher number of infiltrated inflammatory cells. These findings helped to differentiate PD from other similar dermatological conditions such as acne, seborrheic dermatitis, granulomatous rosacea, sarcoidosis, and childhood granulomatous periorificial dermatitis.
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