January 2016 in “Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)” FDG PET/CT can improve cancer treatment plans in dogs.
June 2011 in “Journal of medicine and life science” In this cell study, seaweed extract from Hizkia fusiforme significantly increased the proliferation of dermal papilla cells, suggesting potential for promoting hair growth.
June 2010 in “Journal of Medicine and Life Science” This study suggests that Orostachys iwarenge extract may promote hair growth by increasing the proliferation of dermal papilla cells in an in-vitro setting.
18 citations
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November 2014 in “Journal of Agricultural and Food Chemistry” This study found that ethanol-extracted propolis stimulated hair growth in mice by promoting the proliferation of hair keratinocytes.
12 citations
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May 2014 in “International Journal of Molecular Medicine” This study suggests that the water fraction of Chrysanthemum zawadskii extract promotes hair growth by inducing telogen hair follicles in mice to enter the anagen phase and stimulating cell differentiation.
130 citations
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January 1994 in “Differentiation” In this study, researchers found that bulge cells in mouse hair follicles undergo transient proliferation during early anagen, indicating their role as follicular stem cells. However, another factor beyond dermal papilla proximity may be required to initiate a new anagen phase.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.
60 citations
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March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that RANK-RANKL signaling regulates hair renewal and epidermal homeostasis in mice, revealing its role in initiating hair growth cycles and maintaining skin cell activity.
39 citations
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June 2013 in “Journal of Cosmetic Dermatology” This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.
26 citations
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November 2002 in “Planta medica” In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
24 citations
,
December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
23 citations
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November 2015 in “Phytotherapy Research” This study found that cucurbitacin I from bitter melon most effectively inhibited the growth of lung cancer cells and promoted hair cell growth in cell cultures.
23 citations
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June 2015 in “Oncology Letters” This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.
18 citations
,
April 2019 in “Archives of Dermatological Research” This study found that bovine lactoferrin promotes hair growth in mice by enhancing dermal papilla cell proliferation through the Erk/Akt and Wnt signaling pathways.
17 citations
,
June 2015 in “PLOS ONE” This study reported that FDG PET/CT imaging provided additional information that significantly impacted the treatment and prognosis in seven out of ten canine cancer patients, suggesting its potential in veterinary oncology.
11 citations
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January 2017 in “Oxidative medicine and cellular longevity” This study found that antroquinonol inhibited CD8+ T cell proliferation and reduced proinflammatory cytokine secretion in vitro, while also ameliorating H2O2-induced depigmentation and resisting reductions in hair follicle length, skin thickness, and tyrosinase expression in mice.
4 citations
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September 2010 in “Medical Hypotheses”
3 citations
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June 2017 in “Aesthetic plastic surgery” This study reported that novel adipose slurry injections improved rhytides and dermis density in patients receiving facial wrinkle treatments based on evaluations at multiple follow-up intervals.
2 citations
,
June 2016 in “Journal of Korean Medicine” This study found that low concentrations of Asiasarum heterotropoides extract may enhance proliferation of human mesenchymal stem cells from periodontal tissue without affecting cell morphology.
July 2024 in “Biological and Pharmaceutical Bulletin” This study found that 18-β-Glycyrrhetinic acid, a licorice component, stimulated human hair follicle cell proliferation, inhibited testosterone 5α-reductase, and suppressed TGF-β1, suggesting potential for treating androgenetic alopecia by promoting hair growth and prolonging the anagen phase.
This study found that Wnt7a protein expression increased after corneal epithelial injury and promoted human corneal epithelium cell proliferation by upregulating fibronectin and enhancing cell adhesion.
January 2023 in “Open Life Sciences” This study found that VEGFR-2 activation may play a role in hair follicle differentiation, proliferation, and apoptosis by co-expressing with several key proteins in normal human scalp skin.
71 citations
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January 2019 in “International journal of biological sciences” This study proposes the miR-22-5p-LEF1 axis as a novel pathway that may regulate hair follicle stem cell proliferation.
10 citations
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May 2019 in “BMC Complementary and Alternative Medicine” This study found that Bacillus/Trapa japonica fruit ferment filtrate extracts enhanced human hair follicle dermal papilla cell proliferation through the Akt/ERK/GSK-3β signaling pathway, suggesting potential benefits for alopecia treatment.
8 citations
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May 2017 in “Chinese Journal of Integrative Medicine” Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.
2 citations
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January 2018 in “Biology and medicine” In this study, researchers observed that a significant number of women in Eket, Nigeria, have low testosterone levels, while a subset with high free testosterone may have polycystic ovary syndrome.
1 citations
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August 2023 in “Biomolecules & therapeutics” In this study, researchers found that recombinant human HAPLN1 promoted hair growth in mice and human hair matrix cells by activating specific signaling pathways, suggesting it may offer a potential hair loss treatment with fewer side effects than existing medications.
1 citations
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July 2016 in “Livestock science” This study suggests that nerve growth factor may support hair follicle growth in Liaoning cashmere goats through pathways involving its receptor, TrkA, particularly during the anagen phase.
January 2026 in “Open Life Sciences” This study found that exosomes derived from human amniotic mesenchymal stem cells enhanced stem cell proliferation and structural restoration in irradiated salivary glands of rats, with significant improvements observed by day 7, suggesting activation of the Wnt signaling pathway.
June 2025 in “Jurnal Mandala Pharmacon Indonesia” In this study, researchers found that methanol extract from E. alba stem reduced the expression of the apoptosis marker gene Caspase-3 in T47D breast cancer cells, particularly at 100 ppm, achieving 1.859 times suppression compared to DMSO 2%.