15 citations,
July 2017 in “Hormones” Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
695 citations,
October 2011 in “Cell stem cell” Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
[object Object] 255 citations,
September 2016 in “Frontiers in plant science” Reactive oxygen species (ROS) help control plant growth and development.
100 citations,
November 2017 in “EMBO Reports” Metabolic signals and cell shape influence how cells develop and change.
35 citations,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
3 citations,
December 2019 in “Biomaterials Research/Biomaterials research” Calcium and magnesium in hair increase with age and are higher in adult women.
3 citations,
September 2014 in “SpringerPlus” Human hair loss may have evolved to help increase brain size.
2 citations,
January 2021 in “Cureus” Long-term anabolic steroid use can lead to heart and metabolic health issues.
1 citations,
August 2022 in “International Journal of Molecular Sciences” FGF12 is important for hair growth and could be targeted for hair loss treatment.
May 2024 in “FEBS open bio” Annurca apple extract may help treat hair loss and protect against oxidative stress.
October 2022 in “The Korean Journal of Physiology and Pharmacology” Targeting the PGD2-DP2 pathway may help treat hair loss.
March 2022 in “Molecules” Adenosine can help treat hair loss by promoting hair growth.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
253 citations,
April 2008 in “Current opinion in cell biology” Notch signalling helps skin cells differentiate and prevents tumors.
105 citations,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
81 citations,
February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
75 citations,
February 2017 in “Aging” SkQ1 antioxidant improved health and lifespan in mice.
37 citations,
October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
18 citations,
January 1978 in “Advances in experimental medicine and biology” Hair cystine levels may indicate protein malnutrition, but more research is needed.
[object Object] 11 citations,
July 2021 in “Genetics selection evolution” Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.
10 citations,
September 2022 in “Animals” Certain genes affect udder shape in Holstein cows, important for health and milk production.
7 citations,
March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
6 citations,
December 2022 in “Cell reports” Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
6 citations,
December 2015 in “International journal of immunopathology and pharmacology” AE can have varied symptoms and genetic causes, but zinc therapy helps.
4 citations,
May 2023 in “Cells” Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.
4 citations,
December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
4 citations,
November 2018 in “Journal of comparative pathology” The three adipokines—leptin, adiponectin, and resistin—are present in various cells of normal dog skin.
3 citations,
November 2021 in “Applied Microscopy” Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.
2 citations,
October 2023 in “Biology” Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
2 citations,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.