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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

More research is needed to understand how testosterone is maintained in adult males.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Omega-6 and LDL cholesterol increase the risk of hair loss.

The document explains how male reproductive hormones work and affect the body.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Microorganism overgrowth and hyperkeratosis may trigger immune reactions causing lichen planopilaris.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Key genes can rewire networks, changing skin appendage types.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Resveratrol improved hormone levels, menstrual cycles, hair loss, and ovarian function in PCOS patients.

Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.