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The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.

Extracellular vesicles may effectively treat hair loss with minimal side effects.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Hair in mammals likely evolved from glandular structures, not scales.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Zebrafish are useful for studying and developing treatments for human skin diseases.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Hair follicles help attract immune cells to the skin during stress.

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.