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Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Hair follicles may soon be used more for targeted and systemic drug delivery.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

DHT may increase the risk of heart disease and death in elderly men.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.