13 citations
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September 2020 in “Sensors” This study used melamine formaldehyde particles to measure a pH gradient along the hair shaft, showing a significant pH decrease from the hair sheath to the external shaft.
March 2024 in “Bioimpacts” In this study, curcumin-loaded nanoparticles with a size of 400 nm showed optimal accumulation in human hair follicles after seven days, although mouse models differed significantly in penetration and retention, indicating limitations in their suitability for follicular drug delivery studies.
21 citations
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July 2015 in “International Journal of Nanomedicine” In this study, ultradeformable liposomes containing Tween 20 or terpenes increased phospholipid bilayer fluidity and enhanced skin penetration of sodium fluorescein, with terpenes improving hair follicle penetration.
18 citations
,
October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics” In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.
4 citations
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July 2012 in “Dermatologic Clinics” This article reviews advances in the histologic evaluation of alopecia and hair-related disorders, without presenting new clinical results.
54 citations
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October 2002 in “Journal of controlled release” This study found that increasing a drug's lipophilicity and adding ethanol to the donor phase can enhance its delivery to the hair follicle, although the precise transport mechanism remains unclear.
44 citations
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April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
36 citations
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July 2004 in “Journal of Controlled Release” This study demonstrates that confocal laser scanning microscopy can effectively visualize the rapid diffusion and penetration pathway of a dye into the hair follicle in fresh human scalp skin.
19 citations
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August 2018 in “Journal of the American Academy of Dermatology” In this study, the researchers found that the picosecond pulsed alexandrite laser (PSAL) may be as effective and safe as the Q-switched alexandrite laser (QSAL) for treating freckles in Chinese patients.
16 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review explores new theories, diagnostic tools, and management strategies for primary cicatricial alopecia but reports no new clinical findings.
10 citations
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February 2015 in “Melanoma management” Dermoscopy is useful for many health professionals, not just dermatologists, in improving skin condition diagnoses and reducing unnecessary biopsies.
9 citations
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May 2019 in “Vestnik dermatologii i venerologii” This study demonstrated a method for delivering a photosensitizer, Ammi majus fructuum furocumarines, into hair follicles using calcium carbonate particles, followed by UVA irradiation, which led to significant pigment accumulation, indicating potential improvements for photochemical therapy.
9 citations
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February 2024 in “Indian Dermatology Online Journal” This study discusses the potential of advanced imaging technologies in dermatology to improve diagnostic accuracy and reduce the need for invasive procedures like biopsies, while noting significant barriers in adoption and accessibility in India due to costs and infrastructure constraints.
6 citations
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January 2011 in “PubMed” This paper reviews hair loss associated with various endocrine disorders and describes both traditional and emerging non-invasive diagnostic methods without presenting any new clinical results.
3 citations
,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the epidemiology, risk factors, clinical features, and management of scalp melanomas, highlighting their high mortality rates and specific challenges in diagnosis and treatment; it reports no new research findings.
2 citations
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November 2023 in “Skin Research and Technology” This study found that RCM combined with dermoscopy can differentiate disease states between alopecia areata, tinea capitis, nevus sebaceous, and linear scleroderma of the scalp by identifying distinct dermal and follicular patterns.
2 citations
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August 2013 in “Journal of Investigative Dermatology” This review discusses the dynamic changes in chromatin organization and nuclear morphology during cellular processes like differentiation and disease, highlighting recent advances in understanding these epigenetic mechanisms without presenting new experimental findings.
1 citations
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May 2024 in “Dermatology and Therapy” This review article examines the current understanding of frontal fibrosing alopecia, noting its prevalence in different demographics and the roles of genetic and environmental factors in its pathogenesis, while highlighting that treatment approaches remain varied and lack standardization.
July 2026 in “Diagnostics” This review outlines the key principles and clinical applications of multimodal non-invasive skin imaging technologies, emphasizing their combined strengths in enhancing diagnosis and treatment assessment in dermatology.
February 2026 in “Dermatology and Therapy” This study observed that sonidegib led to a meaningful clinical response in a real-world Chinese cohort with locally advanced basal cell carcinoma, although pathological biopsy remains essential to confirm tumor clearance due to false positives in noninvasive assessments.
August 2024 in “Dermatological Reviews” This review discusses how emerging technologies in dermatology are enhancing the ability to diagnose and treat hair and nail disorders more accurately and effectively, highlighting advancements in both diagnostic techniques and therapeutic methods such as AI-driven technologies that personalize patient care and improve outcomes.
July 2024 in “International Journal of Dermatology” This article highlights the potential of reflectance confocal microscopy for diagnosing and monitoring melasma treatments, and discusses new therapies using oral melatonin, glutathione, and resveratrol, as well as the growing interest in oral minoxidil for alopecia.
September 2023 in “Journal of the American Academy of Dermatology” In this study, a cosmetic product with nano encapsulated cysteamine plus sunscreen significantly improved melasma symptoms and quality of life in adult women over 84 days, compared to sunscreen alone, without any medically relevant intolerance.
This review discusses recent advances in noninvasive hair imaging technologies, such as global photography, trichoscopy, reflectance confocal microscopy, and optical coherence tomography, highlighting their potential to improve hair diagnostics and treatment monitoring, while also outlining their clinical applications and limitations.
January 2017 in “Lasers in Surgery and Medicine” This article introduces a special issue of "Lasers in Surgery and Medicine" focused on dermatology and plastic surgery, but it presents no new research findings.
January 2013 in “Российский журнал кожных и венерических болезней” This study found that intradermal injections of group B vitamins and cystin B6 complex improved scalp circulation, supported hair growth, and reduced hair loss in patients with diffuse alopecia.
159 citations
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July 2014 in “Molecular pharmaceutics” This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.
62 citations
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November 2016 in “Nanoscale” In this study, researchers developed thermoresponsive nanogels that effectively penetrate hair follicles and release a model drug when triggered by temperature, demonstrating greater penetration for medium to large nanogels (300–500 nm) compared to smaller ones.
54 citations
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March 1991 in “Proceedings of the National Academy of Sciences” This study describes a gel-supported in vitro system for culturing skin samples that may effectively replace animal systems for toxicity testing, showing high correlation with in vivo skin toxicity measurements.
50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.