181 citations
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July 2004 in “Journal of controlled release” In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.
97 citations
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September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
27 citations
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March 2018 in “Journal of Experimental Biology” This study found that hair curvature in merino wool is influenced by differences in cell type length rather than the proportions of orthocortical and paracortical cells.
27 citations
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September 2015 in “Drug development and industrial pharmacy” This study demonstrated that adapalene encapsulated in liposomes significantly improved drug delivery to hair follicles compared to gel and drug solution, potentially targeting acne treatment more effectively.
18 citations
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September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.
10 citations
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January 2024 in “Dermatology Research and Practice” This randomized, double-blind, placebo-controlled study found that a supplement containing hydrolysed collagen and vitamin C (Absolute Collagen) improved skin, scalp, and hair over 12 weeks when taken daily or every other day.
4 citations
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October 2012 in “Expert Review of Dermatology” Dermoscopy greatly improves melanoma diagnosis and reduces unneeded surgeries.
2 citations
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December 2018 This study found that dermatoscopy can quickly and non-invasively detect facial vellus hair involvement in patients with alopecia frontal fibrosante, occurring frequently and associated with specific facial lesions.
February 2026 in “Journal of drug targeting” This study found that combining laser ablation with nanoparticulate drug formulations effectively enhanced the skin and follicular delivery of hydrophilic drugs like minoxidil and minocycline in preclinical models.
April 2022 in “Australasian Journal of Dermatology” This case report describes a rare presentation of recurrent plaque psoriasis on the penile shaft, which was controlled with systemic therapy after topical treatments failed.
January 2021 in “Figshare” This study developed a nanostructured lipid carrier for 17-α-estradiol that showed stable physicochemical properties and improved targeting to hair follicles in alopecia treatment.
January 2020 in “Journal of the Brazilian Chemical Society” This study suggests that using nanostructured lipid carriers may improve the targeting of 17-α-estradiol in treating alopecia by improving skin penetration and stability.
20 citations
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September 2018 in “Journal of colloid and interface science” This study found that keratin derivatives with functionalized thiol groups improved binding to both natural and bleached hair fibers, suggesting a promising strategy for enhancing keratin's durability in hair repair.
30 citations
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August 2016 in “Skin research and technology” This study used 3D imaging to reveal age-related reductions in the volumes and connectivity of dermal papillae and rete ridges at the dermal-epidermal junction, which are not fully apparent in 2D examinations.
This review discusses various non-invasive methods for diagnosing alopecia areata, highlighting that trichoscopy signs like short vellus hairs and yellow dots are sensitive indicators of the condition, while advanced imaging techniques provide valuable information on hair follicle status and scalp inflammation.
1 citations
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August 2024 in “Lasers in Surgery and Medicine” This study observed that calcium hydroxylapatite can be successfully incorporated and retained in the dermis for at least six weeks after fractional laser treatment, with new collagen forming around it.
January 2015 in “Hair therapy & transplantation” This review updates on various methods for hair and scalp examination, encompassing non-invasive, semi-invasive, and invasive techniques, and reports no new results.
January 2015 in “SciDok (Saarland University and State Library)” This study confirmed the porcine ear skin model's effectiveness for studying nanoparticle-based drug delivery in human hair follicles, noting particle-dependent uptake and enhancement by massage.
2 citations
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December 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that low frequency sonophoresis may reduce percutaneous absorption of sodium fluorescein-loaded liposomes by partially blocking follicular pathways in the skin.
1 citations
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August 2017 in “British Journal of Dermatology” Sodium hypochlorite can effectively prevent and remove Staphylococcus aureus biofilms in atopic dermatitis at high enough concentrations.
July 2022 in “International Journal of Applied Pharmaceutics” This study concluded that the optimized caffeine-loaded nanostructured lipid carriers improved hair growth by enhancing permeation through skin layers more effectively than an existing market formula.
In this study, Monegy significantly improved hair repair in mice with epilate-induced hair loss, possibly through growth factor induction in hair follicles.
211 citations
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February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
78 citations
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September 2008 in “International Journal of Cosmetic Science” This review outlines various clinical methods for assessing ageing skin and discusses their application in supporting the efficacy claims of anti-ageing treatments, but it reports no new clinical results.
16 citations
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July 2023 in “Frontiers in Medicine” This systematic review provides an in-depth evaluation of non-invasive imaging and biophysical methods for diagnosing and monitoring vitiligo, emphasizing the need for studies with larger sample sizes to verify their use in clinical practice and research.
2 citations
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November 2021 in “Frontiers in Medicine” This article describes current advancements and future possibilities in skin imaging technology, teledermatology, and AI in dermatology, without reporting new research results.
August 2024 in “Skin Research and Technology” This report describes the diagnosis and treatment of traumatic anserine folliculosis in children, highlighting its distinct skin features and suggesting tretinoin cream as an effective remedy.
This article reviews confocal microscopy findings in trichoepithelioma and desmoplastic trichoepithelioma, noting similarities with histological features, but it provides no new clinical results.
4 citations
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July 2023 in “Pharmaceutics (Basel)” This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.
17 citations
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June 2017 in “Journal of pharmaceutical sciences” This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.