TLDR Calcium hydroxylapatite can be successfully integrated into healing skin and stimulates collagen.
This pilot study investigates the intradermal delivery of calcium hydroxylapatite (CaHA) following fractional laser treatment and its impact on tissue integration. Using reflectance confocal microscopy (RCM) and multiphoton microscopy (MPM), researchers observed that CaHA can penetrate and remain in the dermis for at least 6 weeks post-treatment. The study involved treating a volunteer's arm with a fractional erbium laser, with one area also receiving CaHA. Both imaging techniques effectively visualized the distribution and integration of CaHA microspheres, with MPM providing insights into collagen regeneration around the microspheres. The findings suggest that CaHA, a collagen stimulator, can be successfully incorporated into healing skin, and the imaging methods are effective for monitoring treatment progress.
21 citations
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Tailored nonsurgical cosmetic procedures are crucial for safely treating diverse skin types, especially skin of color.
