Genital Dermatology: Case Studies and Research Findings
April 2022
in “
Australasian Journal of Dermatology
”
genital psoriasis Localised Langerhans cell Histiocytosis vulval lichen sclerosus giant condylomata acuminata systemic therapy hydroxyurea subcutaneous adalimumab shave excision curettage cautery Vulval Lichen Sclerosus sequential dermoscopic imaging melanocytic naevi Reflectance confocal microscopy psoriasis Langerhans cell Histiocytosis lichen sclerosus genital warts adalimumab dermoscopy confocal microscopy
TLDR Skin changes during pregnancy are common, and non-invasive imaging is safe for monitoring these changes.
The document discusses various case studies and research findings in genital dermatology, including genital psoriasis, Localised Langerhans cell Histiocytosis of the vulva, severe vulval lichen sclerosus, and giant condylomata acuminata of the penis. Treatments ranged from systemic therapy to hydroxyurea, subcutaneous adalimumab, and shave excision followed by curettage and cautery. The document also includes a consensus statement on managing Vulval Lichen Sclerosus and a prospective controlled trial of sequential dermoscopic imaging of naevi during pregnancy. The trial involved 2095 melanocytic naevi in 40 pregnant women and 31 control women. It found that physiological changes in naevi during pregnancy are common, with dermoscopic parameters changing in 26% of naevi in pregnant women compared to 4.8% in control women. The most common change was enlargement. The study concluded that sequential dermoscopic imaging and Reflectance confocal microscopy are safe, non-invasive techniques to evaluate changing naevi during pregnancy.
