A Review of Aging and an Examination of Clinical Methods in the Assessment of Aging Skin. Part 2: Clinical Perspectives and Methods

    Theresa Callaghan, Klaus‐Peter Wilhelm
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    TLDR The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.
    The 2008 document reviews clinical methods for assessing ageing skin, driven by consumer demand for proof of anti-ageing product efficacy. It covers non-invasive and invasive techniques to measure skin roughness, texture, wrinkles, pigmentation, color, firmness, elasticity, and hair loss. The review details the use of instruments like Fringe Projection, macrophotography, and in vivo confocal microscopy for wrinkle assessment, and video microscopy, colorimetry, and UV-reflectance photography for pigmentation changes. Skin firmness and elasticity are evaluated using the Dermal Torquemeter and Cutometer, while hair loss is assessed by hair growth rates and density. Clinical grading is done by trained technicians using descriptive scales, sometimes alongside invasive procedures. The document emphasizes a disciplined approach to these methods and notes no conflict of interest, as it was fully funded by proDERM.
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