research Influence of Liposome Type and Skin Model on Skin Permeation and Accumulation Properties of Genistein
Elastic liposomes deliver genistein through haired skin better than conventional liposomes.
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research Synthesis and Bioactivity of New Finasteride Conjugate
New Finasteride conjugate improves prostate treatment and vital signs in rats.
research Synthesis of N-Substituted 3-Oxo-17b-Carboxamide-4-Aza-5a-Androstanes and the Tautomerism of 3-Oxo-4-Aza-5-Androstenes
Researchers made two new compounds that could be used for medicine.
research Phytochemical and Pharmacological Investigations of Aftimoon (Cuscuta Reflexa)
Aftimoon (Cuscuta reflexa) has various health benefits, including anti-inflammatory and anticonvulsant effects.
research Toxicological Studies on Procyanidin B-2 for External Application as a Hair Growing Agent
Procyanidin B-2 is safe to use on skin as a hair growth product.
research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research The Effect of Curcumin Supplementation on Circulating Adiponectin and Leptin Concentration in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials
Curcumin supplements increase adiponectin and decrease leptin in adults.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research FCE 28260, A New 5α-Reductase Inhibitor: In Vitro and In Vivo Effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Introduction to the Second Series of Biometals Webinars: The Biology of Mammalian Multi-Copper Ferroxidases and Arsenic Antibiotics
Some bacteria use arsenic compounds as antibiotics, and others have evolved resistance; a particular arsenic-based compound shows potential as a new antimalarial treatment.
research Human Hair Keratin and Its-Based Biomaterials for Biomedical Applications
Human hair keratin can be used in many medical applications.
research 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine
A plant extract was found to effectively block an enzyme related to male hormone-related diseases.
research In Vitro Skin Permeation of Hinokitiol Loaded in Vesicles Composed of Behenyltrimethylammonium Chloride and Stearic Acid
Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.
research Progress on Study of Pharmacological Effects of Procyanidins
Procyanidins may have antioxidant, heart health, cancer-fighting, anti-inflammatory, anti-diabetic, liver-protective, and other health benefits with high efficiency and low toxicity.
research MiR-203a-3p Promotes Loureirin A-Induced Hair Follicle Stem Cells Differentiation by Targeting Smad1
miR-203a-3p helps hair follicle stem cells become specialized by targeting Smad1.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
research Sodium Valproate: Doctor Jekyll and Mister Hyde
Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
research Anti-Androgen Therapy in Dermatology: A Review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research Beta-Catenin Is Involved in Oleanolic Acid-Dependent Promotion of Proliferation in Human Hair Matrix Cells in an In Vitro Organ Culture Model
Oleanolic acid promotes hair growth by increasing cell proliferation through the Wnt/β-catenin pathway.
research ISX9 Loaded Thermoresponsive Nanoparticles for Hair Follicle Regrowth
The new treatment using nanoparticles with ISX9 can effectively regrow hair without major side effects.
research Immunopotentiator from Pantoea Agglomerans 1 (IP-PA1) Promotes Murine Hair Growth and Human Dermal Papilla Cell Gene Expression
IP-PA1 helps grow hair in mice and affects human cell growth-related genes differently than traditional hair growth treatments.
research Development of an Ex Vivo Human Skin Explant Model to Examine Candidate Gene Functions in the Hair Follicle and Epidermis
The model can effectively test gene functions and drug responses in human skin.
research The Fatty Acids and the Skin: A Focus on the N-6 Family of Unsaturated Fatty Acids
Linoleic acid is important for healthy skin, and while most people get enough from their diet, not having enough can cause skin and hair problems.
research Anti-Androgenic Effect of Sesquiterpenes Isolated from the Rhizomes of Curcuma Aeruginosa Roxb.
Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research Rhamnose-Mediated Modulation of Hair Follicle Growth: Insights from Chemical Genomics
Rhamnose may help hair growth and pigmentation, making it a potential treatment for hair loss.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
research Isolation and Structural Identification of a Novel Minoxidil Analogue in an Illegal Dietary Supplement: Triaminodil
A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.
research Graying of Hair Produced by Ingestion of Phenylthiocarbamide
Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
research Baicalin Inhibits Recruitment of GATA1 to the HSD3B2 Promoter and Reverses Hyperandrogenism of PCOS
Baicalin may help reduce excessive male hormone levels in PCOS.