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Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

New therapies are being developed that target integrin pathways to treat various diseases.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

Non-coding RNAs could help detect and treat radiation damage.

Nanotube-based hair treatments could improve hair health and growth, and offer long-lasting effects.

Certain RNA molecules are important for the development of wool follicles in sheep.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Stress can cause early aging in certain skin cells, leading to problems with hair growth.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

cDermo-1 causes dense skin, feathers, and scales in chickens.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Tailored treatments for alopecia areata are recommended based on severity and patient needs.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

VB-1, a natural compound, may promote hair growth by enhancing a key cell growth pathway.