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    Glossary Co-culture

    growing two or more cell types together for interaction study

    Co-culture, also known as coculture or co culture, refers to the practice of growing two or more different types of cells together in the same environment. This technique is used to study interactions between different cell types, such as how hair follicle cells interact with skin cells, which can provide insights into biological processes and disease mechanisms, including conditions like alopecia.

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    1. Co‐culture of Human Hair Follicles and Dermal Papillae in a Collagen Matrix The Journal of Dermatology · 1990 · 36 citations
    2. Comparison Treatment of Vitiligo by Co-culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without NB-UVB 2020
    3. 600 Differential Molecular Signature of Dermal Papilla Cells (DPCs) from Balding and Non balding Scalp in 2D, 3D culture and Co-culture with Adipose-derived stem cells (ASCs) Journal of Investigative Dermatology · 2019
    4. Coculture of Human Hair Follicles and Dermal Papillae in Type I Collagen Gel Annals of the New York Academy of Sciences · 1991 · 7 citations
    5. Epithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy Stem Cell Research & Therapy · 2020 · 48 citations
    6. 3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing Stem Cell Research & Therapy · 2020 · 17 citations
    7. High-throughput screening of 3D co-culture hair follicle mimetic tissue with enhanced ECM for the screening of hair growth promoting compounds Biomaterials Research · 2024
    8. 3D Co-Culture model of Endothelial Colony Forming Cells (ECFCs) Reverses Late Passage Adipose-derived Stem Cell Senescence for Wound Healing Research Square (Research Square) · 2020
    9. Organotypic Cocultures as Models to Study Cell-Cell and Cell-Matrix Interactions of Human Hair Follicle Cells Skin Pharmacology and Physiology · 1994 · 18 citations
    10. Restoration of hair-inductive activity of cultured human follicular keratinocytes by co-culturing with dermal papilla cells Biochemical and Biophysical Research Communications · 2018 · 14 citations
    11. Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening Advanced Healthcare Materials · 2025
    12. 329 In vitro co-culture models of merkel cell-neurite complex in touch domes Journal of Investigative Dermatology · 2021
    13. Perifollicular vascularization: Cocultures and tricultures approaches to study the cross-talk between microvascular endothelial cells, follicle papilla cells and keratinocytes Vascular Pharmacology · 2015
    14. Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers Journal of Biomaterials Science Polymer Edition · 2020 · 11 citations
    15. Effect of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Nanofiber Matrices Cocultured With Hair Follicular Epithelial and Dermal Cells for Biological Wound Dressing Artificial Organs · 2007 · 64 citations
    16. Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel Annals of translational medicine · 2022 · 4 citations
    17. Proliferation and differentiation of organoid hair follicle cells co-cultured with fat cells in collagen gel matrix culture British Journal of Dermatology · 1998 · 30 citations
    18. Physiological Doses of Red Light Induce IL‐4 Release in Cocultures between Human Keratinocytes and Immune Cells Photochemistry and Photobiology · 2017 · 9 citations
    19. Growth of Nerve Fibers to Merkel Cells Observed in Co-Culture of Sensory Ganglia and Sinus Hair Follicles 2003 · 1 citations
    20. 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts Journal of Investigative Dermatology · 2020
    21. Attraction of sensory fibers by Merkel cells during co-culture of sensory ganglia and hair follcies in collagen-gel Neuroscience Research · 2000
    22. Effects of the biomimetic peptide Sh-Polypeptide 9 (CG-VEGF) on cocultures of human hair follicle dermal papilla cells and microvascular endothelial cells Experimental Dermatology · 2015 · 7 citations
    23. The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture Experimental dermatology · 2008 · 68 citations
    24. Immortalized Rat Whisker Dermal Papilla Cells Cooperate with Mouse Immature Hair Follicle Buds to Activate Type IV Procollagenases in Collagen Matrix Coculture: Correlation with Ability to Promote Hair Follicle Development in Nude Mouse Grafts Journal of Investigative Dermatology · 1995 · 11 citations
    25. Evaluation of the Effect of Plant Mixture Ethanol Extracts Containing Biota orientalis L. Extract on Suppression of Sebum in Cultured Sebocytes and on Stimulation of Growth of Keratinocytes Co-cultured with Hair Papilla Cells Cosmetics · 2017 · 4 citations
    26. The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse Methods in molecular biology · 2019 · 2 citations
    27. Culture of pyramidal neural precursors, neural stem cells, and fibroblasts on various biomaterials Journal of Biomaterials Science, Polymer Edition · 2018 · 3 citations
    28. Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions Cell Proliferation · 2021 · 7 citations
    29. 583 RNA sequencing of immortalised balding and non balding DPCs identifies potential balding gene signatures Journal of Investigative Dermatology · 2022
    30. Would you recognize this lesion as a gumma syphilitica? Journal of The American Academy of Dermatology · 2017