Comparison Treatment of Vitiligo by Co-Culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without Narrowband UVB

January 2020

Amany A. Saleh, Osama H Abdel-salam, Hala G Metwall, Hany A Abdelsalam, A. A. Hassan, Walaa S Sosa

vitiligo melanocytes hair follicles adipose-derived stem cells Narrowband UVB NB-UVB pigmentation co-culture stem cells UVB light

TLDR Treating vitiligo with stem cells and melanocytes from hair, along with UVB light, works better than without the light.

In the study, two groups of patients with stable, resistant vitiligo were treated using a co-culture of adipose-derived stem cells and melanocytes derived from hair follicles. Group A was exposed to Narrowband UVB (NB-UVB) light, while Group B was not. After a follow-up period of 3 months, Group A exhibited a significantly better pigmentation response compared to Group B. The study concluded that the co-culture method, especially when combined with NB-UVB light exposure after treatment, is a safe and effective treatment for stable localized vitiligo in patients who are resistant to other therapies. Factors such as the stability, size, site, and onset of vitiligo were important in affecting treatment outcomes.

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