Restoration of Skin Pigmentation After Deep Partial or Full-Thickness Burn Injury

    January 2018 in “ Advanced drug delivery reviews
    Niann‐Tzyy Dai, Hsin‐I Chang, Yiwen Wang, Keng-Yen Fu, Tai-Chun Huang, Nien-Chi Huang, Jhen-Kai Li, Pai‐Shan Hsieh, Lien-Guo Dai, Chao-Kuei Hsu, Peter Maitz
    TLDR The review suggests that there are various treatments to help restore skin color after severe burns.
    The review discussed the significant impact of deep partial or full-thickness burn injuries on skin pigmentation, particularly in darker-skinned individuals from African and Asian populations. It highlighted the mechanisms of repigmentation, including the roles of melanocytes and melanocyte stem cells, and the challenges posed by severe burns that destroy these cells. The review also covered various therapeutic strategies for treating pigmentation disorders, such as surgical skin grafting, laser treatments, and emerging skin tissue-engineering techniques. The need for further research to develop effective treatments for pigmentation restoration was emphasized.
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