Hairless Descendants of Mexican Hairless Dogs: An Experimental Model for Studying Hypertrophic Scars
November 2011
in “
Journal of Cutaneous Medicine and Surgery
”
Studysummary The researchers concluded that hairless dogs can serve as an effective model for studying hypertrophic scarring due to their development of scars with morphological similarities to human hypertrophic scars.
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The study explored the use of hairless dogs as a model for human hypertrophic scarring by creating full-thickness wounds on their dorsolumbar skin. The resulting scars were similar to human hypertrophic scars, showing hyperpigmentation, increased activated melanocytes, and collagen and elastic fiber remodeling. These results indicated that hairless dogs could be a suitable model for further research on hypertrophic scarring in humans.
