research Genome Wide Association Analysis of Root Hair Traits in Rice Reveals Novel Genomic Regions Controlling Epidermal Cell Differentiation
Scientists found new genetic areas that affect how rice root hairs grow and develop.
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330-360 / 1000+ results research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An In Silico and In Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Homozygous Whole Body Cbs Knockout in Adult Mice Features Minimal Pathology During Aging Despite Severe Homocysteinemia
Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research Selective Delivery of Tofacitinib Citrate to Hair Follicles Using Lipid-Coated Calcium Carbonate Nanocarriers Controls Chemotherapy-Induced Alopecia Areata
A new treatment using nanoparticles can effectively prevent and reduce hair loss caused by chemotherapy.
research Effect of the Multifunctional Cosmetic Ingredient Sphinganine on Hair Loss in Men and Women with Diffuse Hair Reduction
Sphinganine can reduce hair loss and improve scalp health.
research Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research Anti-Alopecia Activity of Alkaloids from Noni Fruit Against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies
Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter
MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
research Exploring the Gut Microbiome and Metabolome in Individuals with Alopecia Areata
Alopecia Areata is linked to specific gut bacteria and metabolites, indicating a complex gut microbiome.
research Antiviral Drugs Prolong Survival in Murine Recessive Dystrophic Epidermolysis Bullosa
Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
research Treatments for Alopecia Areata: A Network Meta-Analysis
The medicine baricitinib was found to notably improve hair regrowth in alopecia areata, but more research is needed on its side effects and other treatments.
research Drug Repurposing: A Promising Approach for Patients With Angina and Non-Obstructive Coronary Artery Disease (ANOCA)
Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
research Deep Hair Phenomics: Implications in Endocrinology, Development, and Aging
A new tool can analyze hair to detect changes due to hormones, genetics, and aging.
research Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata
Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Distinct Phenotypic and Genomic Signatures Underlie Contrasting Pathogenic Potential of Staphylococcus Epidermidis Clonal Lineages
Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.
research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
research Quality of Life Assessment in Patients with Androgenetic Alopecia
Androgenetic alopecia significantly harms quality of life, affecting emotions and relationships.
research Two-Ligand Priming Mechanism for Potentiated Phosphoinositide Synthesis Is an Evolutionarily Conserved Feature of Sec14-Like Phosphatidylinositol and Phosphatidylcholine Exchange Proteins
A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.
research Identification of Drug-Disease Associations Using Information of Molecular Structures and Clinical Symptoms via Deep Convolutional Neural Network
A new model can predict drug-disease links well, helping drug research.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Long-Term Outcome After Hand and Forearm Transplantation: A Retrospective Study
Hand and forearm transplants can be successful long-term, but they come with challenges like rejection and side effects from immunosuppression.
research Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross-Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof
Coconut seed extract may effectively treat scabies in rabbits by killing mites and reducing inflammation.
research Single-Cell Transcriptomics Reveals a Senescence-Associated IL-6/CCR6 Axis Driving Radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.