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The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Relatives of women with PCOS symptoms are more likely to have similar health issues.

Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

A certain genetic variation is linked to a higher risk of polycystic ovarian syndrome.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

A genetic variant in the androgen receptor gene increases heart disease risk in women but not in men.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Mutation in hairless gene may increase hair loss risk.

The document does not determine if adults with aphallia are fertile.

AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.

FLCN helps control iron levels in cells.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

A new gene mutation causes insulin resistance in a girl and her mother.

A new gene variant causes glucocorticoid resistance in a mother and son.

People with Down syndrome have higher rates of certain immune-related conditions and need special medical attention.