Androgenetic Alopecia in Heterozygous Carriers of a Mutation in the Human Hairless Gene

    Eli Sprecher, Adel Shalata, Kamal Dabhah, Boris Futerman, Shai Lin, Raymonde Szargel, Reuven Bergman, Rachel Friedman-Birnbaum, Nadine Cohen
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    TLDR Mutation in hairless gene may increase hair loss risk.
    This document is a collection of summaries of various studies on the relationship between the hairless gene and androgenetic alopecia (AGA). The studies suggest that carrying a mutation in the hairless gene may increase the likelihood of developing AGA, but more research is needed to fully understand the role of this gene in hair loss. The hairless gene is important for hair growth and development, and disruption of this gene can prevent hair follicles from starting a new cycle. The studies emphasize the need for genetic testing in individuals with a family history of hair loss to identify carriers of the mutation.
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