The Hairless Gene in Androgenetic Alopecia: Results of a Systematic Mutation Screening and a Family-Based Association Approach

    April 2002 in “ British Journal of Dermatology ”
    Axel M. Hillmer, Rudolf Kruse, Fabio Macciardi … Sven Cichon
    Studysummary This study found no strong evidence that the human hairless gene is significantly involved in the development of androgenetic alopecia, though a minor role cannot be completely ruled out.
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    Research cited in this study 10

    1. Variant 1859G→A (Arg620Gln) of the Hairless Gene: Absence of Association with Papular Atrichia or Androgenetic Alopecia American Journal of Human Genetics · 2001
    2. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    3. Reply Journal of Investigative Dermatology · 2000
    4. Androgenetic Alopecia in Heterozygous Carriers of a Mutation in the Human Hairless Gene Journal of The American Academy of Dermatology · 2000
    5. Novel Hairless Mutations in Two Kindreds with Autosomal Recessive Papular Atrichia Journal of Investigative Dermatology · 1999
    6. Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia Journal of Investigative Dermatology · 1999
    7. A Missense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia in a Family of Irish Travellers The American Journal of Human Genetics · 1998
    8. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998
    9. Alopecia Universalis Associated With a Mutation in the Human Hairless Gene Science · 1998
    10. The Inheritance Of Common Baldness: To Be Or Not To Be? Journal of the American Academy of Dermatology · 1984