May 2025 in “Preprints.org” This study identified a unique circulating microRNA signature associated with severe alopecia areata, distinguishing it from other inflammatory skin conditions and suggesting these miRNAs as non-invasive biomarkers for diagnosis and potential therapeutic targets.
April 2025 in “Frontiers in Genetics” This study found that integrating breed-specific BOA and SNP-based models helps reveal the genetic factors involved in thermotolerance traits in beef cattle, enhancing insights into thermoregulation and potentially improving cattle's heat resilience.
April 2025 in “International Journal of Health Sciences” This study reports that Polyscias scutellaria exhibits diverse pharmacological activities, including antibacterial, antifungal, anti-inflammatory, antioxidant, and antidiabetic properties, suggesting potential therapeutic uses in various health applications.
February 2025 in “International Journal of Molecular Sciences” In this study, maternal melatonin implantation in pregnant rabbits reduced hair follicle cell apoptosis and increased hair follicle density in their neonatal offspring, suggesting a beneficial impact on hair follicle development mediated through specific molecular pathways.
February 2025 in “Stem Cell Research & Therapy” This review highlights the critical role of mitochondrial dysfunction in hair loss, particularly androgenetic alopecia, and explores potential therapies targeting mitochondrial pathways to improve hair health, underscoring the need for further research in this area.
This review highlights the increasing global incidence and broad socio-economic impact of celiac disease, emphasizing the need for improved recognition and management to address its multidimensional implications, including comorbidities and dietary challenges.
January 2025 in “Journal of Clinical Medicine” This study found that among Portuguese women with hirsutism, polycystic ovary syndrome was the most prevalent cause, associated with distinct hormonal features and higher BMI compared to controls.
January 2025 in “Journal of Personalized Medicine” This study found that patients with alopecia areata had a higher prevalence of prediabetes and obesity compared to healthy controls, suggesting the importance of regular screening and early management of these conditions in this population to mitigate associated health risks.
December 2024 in “PLoS ONE” In this study, researchers observed that alopecia prevalence varies in gray bats throughout the summer, with higher rates in lactating females, who also exhibit more severe lesions, but found no link between subcutaneous mites and fur loss.
November 2024 in “Journal of Cosmetic Dermatology” This study found that a hair serum with plant-derived ingredients significantly reduced hair loss in women with chronic telogen effluvium over 16 weeks, and was well-tolerated, leading to improved hair characteristics and quality of life compared to a control group.
November 2024 in “Forensic Sciences” This review highlights the potential for using the Y chromosome in epigenetic analyses to better understand male-specific aging and disease mechanisms.
This study investigated the potential mechanisms of Curcuma aeruginosa in treating androgenetic alopecia and identified 66 bioactive compounds interacting with proteins involved in the disorder, suggesting its involvement in hormone response and specific signaling pathways.
March 2024 in “Current issues in molecular biology” This literature review explores the role of biomarkers in personalized medicine for various dermatological conditions like Hidradenitis Suppurativa, Psoriasis, and Atopic Dermatitis, highlighting how they guide targeted therapies and the limitations of current markers in specificity, as reported by the authors.
March 2024 in “Antioxidants” This study examines the effects of excessive or prolonged exposure to blue light on retinal function and highlights its potential health implications, noting that both photoreceptor and intrinsically photosensitive retinal ganglion cells (ipRGCs) are particularly sensitive to blue wavelengths.
January 2024 in “Biotechnology advances” This review highlights the importance of selecting high-quality bioassays in discovering bioactive compounds from marine sources, emphasizing their role in evaluating safety and efficacy during pharmaceutical, food supplement, and cosmetic development.
June 2023 in “Pharmaceuticals” This review reports that sex-related differences in pharmacological response have been observed in SARS-CoV-2 infection, dyslipidemia, and diabetes mellitus, with implications for treatment strategies; for example, men may respond better to genomic vaccines for SARS-CoV-2, while women may benefit more from certain antiviral medications.
January 2023 in “International Journal of Molecular Sciences” This review discusses the biologically active compounds in Maxillariinae orchids, highlighting 62 semiochemicals with medical potential, but reports no new clinical findings.
October 2022 in “BMC genomics” This study investigated adenosine-to-inosine RNA editing in the hair follicle cycle of Tianzhu white yak, identifying numerous editing sites and suggesting their involvement in pathways related to hair growth.
October 2022 in “Frontiers in Genetics” This study found that miRNAs increase and target mRNAs and lncRNAs decrease from the anagen to telogen phase in mouse hair follicles, and these ceRNA networks may play a role in hair follicle cycling.
February 2023 in “Pharmaceutics” This study found that oral administration of 7, 8–dihydroxyflavone in guinea pigs improved recovery from gentamicin-induced vestibular damage, suggesting potential therapeutic use for vestibular dysfunction in humans.
October 2022 in “Biomolecules” This study found that in male rats, chronic finasteride treatment reduced allopregnanolone levels, which, upon drug withdrawal, correlated with increased pro-inflammatory cytokines and altered neurotransmitter levels.
22 citations
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August 2015 in “Cochrane Database of Systematic Reviews” The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.
13 citations
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February 2012 in “International Journal of Dermatology” This case report identifies a novel nonsense mutation in the CDH3 gene associated with hypotrichosis and juvenile macular dystrophy.
16 citations
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September 2008 in “Dermatologic Therapy” This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.
1 citations
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January 1994 in “The Journal of Dermatologic Surgery and Oncology” This article has no abstract and provides no new results; it is likely a narrative or commentary on chemical peels.
126 citations
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October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
5 citations
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November 2005 This review discusses the applications of confocal laser scanning microscopy in visualizing fluorescent compounds within the skin, noting its potential for tracking drug carriers and enhancing penetration studies, but reports no new results.
March 2022 in “Indian Journal of Animal Research” In this study, canine hair follicle stem cells were shown to be multipotent, capable of differentiating into various cell types like adipocytes in vitro.
227 citations
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December 2021 in “ACS Nano” This review discussed the potential of multifunctional photoresponsive hydrogels for wound regeneration, highlighting various types prepared with diverse photosensitizers and photothermal/photodynamic agents, and explored their role in modulating bacterial microenvironments to inhibit infection and promote healing.
25 citations
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July 2019 in “Journal of drug delivery science and technology” This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.