291 citations
,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
34 citations
,
October 2011 in “Pathology Research International” This article reviews potential factors influencing Behçet's disease, like increased neutrophil functions, immunological changes, stress, and hormonal alterations, but it presents no new clinical results.
12 citations
,
February 2006 in “Lipids” This study found that in Japanese, German, and American females, changes in hair lipid patterns with age may reflect alterations in sebum excretion and affect hair texture.
4 citations
,
January 2006 in “International Journal of Cosmetic Science” This study found that scanning electron microscopy with argon sputter etching visualizes hair lipids at the cell membrane complex as distinctive convex structures, shedding light on their role and localization in human hair.
7 citations
,
December 2013 in “The Journal of Dermatology” This article is a letter to the editor discussing hair graying and loss potentially induced by imatinib mesylate, but it does not provide new research results.
June 2008 in “Experimental dermatology” This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.
67 citations
,
September 2017 in “Journal of Open Innovation Technology Market and Complexity” This paper describes how market and social forces impact the development of social innovations, offering ways to bridge social gaps by engaging youth and connecting corporations with communities.
1 citations
,
October 2022 in “Journal of Bioscience and Bioengineering” This study found that Y27632 treatment facilitated the formation of core-shell-shaped hair follicle organoids, resulting in nearly 100% efficient hair shaft sprouting in vitro.
April 2017 in “Journal of Dermatological Science” In this study, both 2.5% benzoyl peroxide gel and 0.1% adapalene gel exhibited comedolytic effects on the spontaneous comedogenic rhino mouse model.
November 2016 in “Regenerative Medicine” This article compiles stem cell and regenerative medicine developments from industry press releases in September 2016, reporting no new study results.
82 citations
,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
5 citations
,
June 2022 in “Biophysical Journal” This study used a probabilistic Boolean network model to explore hair follicle cell fate regulation and predicted that varying TGF-β levels, in coordination with BMP and TNF, can influence either apoptosis or cell proliferation during different follicle growth stages.
236 citations
,
April 2015 in “Cell” This study found that patterned hair plucking in mice triggers a collective regeneration response in nearby unplucked hair follicles via a quorum sensing mechanism involving immune signaling.
47 citations
,
November 2012 in “Pharmaceutical research” This study found that surface modified nanoparticles showed increased skin permeation and improvement in allergic contact dermatitis, independent of the follicular pathway.
29 citations
,
July 1991 in “Biochimica et Biophysica Acta (BBA) - General Subjects” Glycoproteins are present in the cell membranes of various keratin fibers.
27 citations
,
July 1990 in “International Journal of Dermatology” In this controlled study, a pulsed electrical field treatment significantly increased hair regrowth compared to baseline and the control group over 36 weeks, without observed side effects.
20 citations
,
September 2010 in “Cell Cycle” This study reports that in MRL mice, loss of p53 does not impair ear regeneration, suggesting p21's potential role in this process may involve the Tgfb/Smad pathway.
5 citations
,
July 2013 in “Our Dermatology Online” This study found that lichen planopilaris was the most common variant of cicatricial alopecia among patients, with perifollicular fibrosis being a prevalent histopathological feature.
3 citations
,
September 2005 in “International Journal of Cosmetic Science” This study found that monounsaturated oils like olive oil penetrate hair fibers effectively, whereas polyunsaturated oils typically do not penetrate beyond the cuticle.
October 2025 in “Plastic & Reconstructive Surgery” This study evaluated the safety and effectiveness of MNC-QQ cell therapy in five men with androgenic alopecia, reporting no adverse effects and improvements in hair growth, hair density, and quality of life over six months.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
401 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.
380 citations
,
March 2000 in “Proceedings of the National Academy of Sciences” This study demonstrates that mice with ectopic expression of the human GLI-1 gene in their skin developed tumors resembling human basal cell carcinoma, suggesting that GLI-1 is central to tumor development without additional p53 or Ha ras mutations.
333 citations
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March 2000 in “Proceedings of the National Academy of Sciences” In this study, researchers established that increased expression of the human GLI-1 gene in mouse skin leads to the development of tumors that closely resemble human basal cell carcinomas, without requiring additional mutations in the p53 or Ha ras genes.
269 citations
,
October 2017 in “International Journal of Molecular Sciences” This review examines the challenges of cell engraftment in regenerative medicine and discusses potential strategies to improve the efficacy of cell-based therapies, including cell-free regenerative approaches.
182 citations
,
August 2016 in “Development” This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.
182 citations
,
May 2003 in “Development” This study found that Myc activation in mouse epidermis impairs keratinocyte adhesion and motility by downregulating extracellular matrix and cytoskeleton proteins, affecting hair lineage differentiation.
100 citations
,
November 2017 in “EMBO Reports” This review discusses the roles of metabolism, reactive oxygen species, intracellular pH, and cell morphology in influencing cell fate decisions during stem cell differentiation but reports no new experimental results.
85 citations
,
January 2018 in “Cell stem cell” This study found that synchronized signals in the microenvironment regulate stem cell lineage choices in hair follicles by influencing chromatin dynamics during regeneration.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.