Acquired Immunogenicity of DNA After Modification with Malondialdehyde in Patients with Alopecia Areata

    March 2014 in “ Scandinavian journal of clinical and laboratory investigation ”
    Abdullateef A. Alzolibani, Zafar Rasheed, Ahmad A. Al Robaee
    Studysummary This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.
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    Research cited in this study 13

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    2. Alopecia Areata Update Dermatologic Clinics · 2012
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    4. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    5. Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata British Journal of Dermatology · 2011
    6. Etiopathogenesis of Alopecia Areata: Why Do Our Patients Get It? Dermatologic therapy · 2011
    7. Trichohyalin Is a Potential Major Autoantigen in Human Alopecia Areata Journal of Proteome Research · 2010
    8. Autoimmunity: Alopecia Areata Journal of Investigative Dermatology Symposium Proceedings · 2004
    9. Characterization of Hair Follicle Antigens Targeted by the Anti-Hair Follicle Immune Response Journal of Investigative Dermatology Symposium Proceedings · 2003
    10. Keratin 16 Expression Defines a Subset of Epithelial Cells During Skin Morphogenesis and the Hair Cycle Journal of Investigative Dermatology · 2002
    11. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002
    12. Antinuclear And Antithyroid Antibodies In 68 Japanese Patients With Alopecia Areata Dermatology · 1999
    13. Failure of Passive Transfer of Serum From Patients With Alopecia Areata and Alopecia Universalis to Inhibit Hair Growth in Transplants of Human Scalp Skin Grafted Onto Nude Mice British Journal of Dermatology · 1992