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This study reports that mutations in human L-PGDS affect the entrance and exit of ligands in its binding cavity, suggesting these residues play a role in ligand interaction processes.

This commentary discusses ethical concerns with direct-to-consumer teledermatology services, highlighting potential conflicts of interest and issues with care quality.

This study found that in genetically diabetic mice, supplementation with safflower or evening primrose oil prevented the decrease in certain fatty acids and improved skin conditions, but increased plasma glucose levels.

In this study, researchers investigated a new local drug delivery system using glycol chitosan hydrogel and doxorubicin (GC10/DOX) for thyroid cancer in mice, finding it produced a stronger antitumor effect compared to conventional treatment methods.

This study found that Diabetex significantly improved wound healing and reduced fasting blood sugar in diabetic rats, showing potential as a safe and economic treatment strategy for diabetic-resistant wounds.

This study suggests that dermal stem/progenitor cells can be enriched by intracellular granularity and display high proliferation and differentiation potential in vitro, distinguishing them from other fibroblasts and progenitors.

This study reports that a novel series of compounds can potently and selectively inhibit glycogen synthase kinase-3, which activates glycogen synthase in insulin receptor-expressing cells and primary rat hepatocytes.

This systematic review found that oral nutraceuticals significantly improved various measures of hair growth compared to placebo, but concluded that more rigorous research is needed to confirm these findings.

This study found that growth factor concentrate provides quicker improvements for patterned hair loss, but platelet-rich plasma offers more sustained benefits after treatment.

This study found that vitamin D supplementation significantly improved clinical pregnancy rates in women with polycystic ovary syndrome treated at a Turkish infertility clinic, though it did not affect live birth or miscarriage rates.

This review describes how recent discoveries in genetic defects and alternative pathways in androgen biosynthesis are reshaping our understanding of male sexual differentiation, but it presents no new clinical findings.

In this study, researchers developed ionizable coenzyme Q10-engineered lipid/fiber microplexes that restored mitochondrial-ribosomal function and enhanced mRNA translation in senescent cells, leading to increased hair follicle density and bone formation in mouse models compared to conventional lipid nanoparticles.

This case study describes a severe instance of iatrogenic Cushing's syndrome induced by gamma-hydroxybutyric acid, exacerbated by combined use of betamethasone and anabolic steroids, in an HIV-positive patient on cobicistat-containing therapy.

This study found that DGAT1 exhibits additional acyltransferase activities in vitro, including MGAT, wax synthase, and ARAT activities, suggesting these could be relevant to its in vivo functions.

This study suggests that combining GliSODin(®) Skin Nutrients with tazarotene cream significantly benefits facial fine wrinkles, photodamage, moisture, and elasticity compared to tazarotene alone.

This review discusses the diagnosis and treatment of 21-hydroxylase deficiency in congenital adrenal hyperplasia and emphasizes the need for earlier detection and proper management; it reports no clinical results.

In this in-vitro study, researchers identified finasteride as the most effective FDA-approved drug for expanding functional myeloid-derived suppressor cells, suggesting its potential future use in immunosuppressive therapies.

The lotion CG428 did not show effectiveness in treating permanent hair loss in breast cancer survivors.

This study provides a comprehensive platform to explore stem cell interactions regulating hair follicle growth, revealing key signaling pathways in epithelial-mesenchymal interactions using advanced RNA sequencing and transgenic reporters.

This study found that aminoguanidine induced increased VEGF mRNA expression in stored hair follicle micrografts, suggesting potential for developing growth-promoting storage solutions in hair restoration surgery.

In this study, the addition of a topical gel containing growth-factor mimicking oligopeptides and other ingredients showed improved efficacy in subjects with androgenic alopecia using minoxidil or finasteride compared to drug treatment alone.

This study found that L-cystine, D-pantothenat, and miliacin can enhance the metabolic capacity and proliferation of human keratinocytes, with a combination of these additives potentially providing synergistic benefits in growth media.

The researchers reported that glucuronides stored as dried blood spots under ambient conditions exhibited stability equivalent to liquid samples stored at -80°C.

This review examines the effects of adipose-derived stem cells and their secreted factors on hair growth stimulation in laboratory and animal models, suggesting their potential as therapeutic agents for hair loss treatment.

In this study, the analysis of Ukraine's pharmaceutical market from 2020 to 2023 found a large variety of Vitamin D3 preparations, predominantly domestic and synthetic, with capsule forms being common; consumer surveys highlighted that doctor recommendations strongly influenced purchasing decisions.

This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.

This study synthesized and compared single-ion doped silicate bioactive glass nanoparticles for tissue repair, finding that BSr and BCe were most effective in accelerating wound healing and restoring vasculature, with BSr particularly reducing inflammation and BCo enhancing hair follicle regeneration but with limited biosafety window.

This study found that dexamethasone treatment reduced cell viability and growth factor expression in human dermal papilla cells, suggesting it inhibits hair growth.

This study found that Cynatine HNS significantly improved hair and nail health in women after 90 days compared to placebo.

This report describes two cases of glucocorticoid resistance syndrome highlighting genetic diversity; one patient improved with low-dose dexamethasone despite negative genetic testing, while the other is monitored with a novel NR3C1 variant.