Effects of Glucocorticoid on Human Dermal Papilla Cells In Vitro

    December 2012 in “ The Journal of Steroid Biochemistry and Molecular Biology ”
    Soon‐Jin Choi, A‐Ri Cho, Seong Jin Jo … Ohsang Kwon
    Studysummary This study found that dexamethasone treatment reduced cell viability and growth factor expression in human dermal papilla cells, suggesting it inhibits hair growth.
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    Research cited in this study 13

    1. Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro Journal of Korean Medical Science · 2007
    2. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006
    3. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    4. Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression Journal of Investigative Dermatology · 2005
    5. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002
    6. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    7. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    8. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996
    9. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996
    10. A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A Journal of Investigative Dermatology · 1994
    11. Glucocorticoid Effect on Hair Growth Initiation: A Reconsideration Skin Pharmacology and Physiology · 1993
    12. Androgens and the Hair Follicle: Cultured Human Dermal Papilla Cells as a Model System PubMed · 1991
    13. Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin Journal of Investigative Dermatology · 1990

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    3. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    4. Hair Follicle Reformation Induced by Dermal Papilla Cells from Human Scalp Skin Archives of Dermatological Research · 2006
    5. Study on Hair Follicle Formation Induced by Dermal Papilla Cells Chinese Journal of Reparative and Reconstructive Surgery · 2003
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