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120-150 / 362 results![Cytoprotective role of human dental pulp stem cell-conditioned medium in chemotherapy-induced alopecia](/images/research/6fef318b-632b-4fb3-8b7e-5422939d19dd/small/35328.jpg)
research Cytoprotective role of human dental pulp stem cell-conditioned medium in chemotherapy-induced alopecia
Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
![Nanotechnology-based techniques for hair follicle regeneration](/images/research/77769bc6-2511-4120-845a-190802fc7f30/small/19039.jpg)
research Nanotechnology-based techniques for hair follicle regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Cell Population Dynamics in Wound-Induced Hair Follicle Neogenesis Model
![Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches](/images/research/431f4741-73eb-4b7d-ad19-c8e95caf39b3/small/35591.jpg)
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis
Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
research Lrig1 Expression in Human Sebaceous Gland Tumors
Lrig1 could be a marker for advanced sebaceous carcinoma.
![Fibroblast heterogeneity: implications for human disease](/images/research/7cdf0ea5-e0cf-46e9-b61c-a9b319032217/small/20225.jpg)
research Fibroblast heterogeneity: implications for human disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Molecular Targeted Agents and Biologic Therapies for Non-small Cell Lung Cancer
New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
![Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease](/images/research/8bd8c348-0d6d-4846-a4b0-c23dfd8edf94/small/35798.jpg)
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
![Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation](/images/research/702c720c-02b2-4fef-b9f1-2d456bd34c18/small/36172.jpg)
research Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation
Thymic transplantation normalized some T-cells but not others, maintaining immune function.
![Emerging roles of transit‐amplifying cells in tissue regeneration and cancer](/images/research/0b88b50f-ff0a-4dbc-a64e-79fc6b499344/small/19529.jpg)
research Emerging roles of transit‐amplifying cells in tissue regeneration and cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
![Plumbagin, a Natural Compound with Several Biological Effects and Anti-Inflammatory Properties](/images/research/8267edba-1d31-4dd0-bc03-53ac55fe4a6f/small/20616.jpg)
research Plumbagin, a Natural Compound with Several Biological Effects and Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
![Differential impact of environmental factors on systemic and localized autoimmunity](/images/research/bf67fac9-e9b4-4c01-9595-132cb93c63cc/small/27231.jpg)
research Differential impact of environmental factors on systemic and localized autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
![Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease](/images/research/c6ae78d6-5249-45ef-828f-57ac01b15a6f/small/36381.jpg)
research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease
Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
![NEW CHALLENGE TO CANCER AND LONGEVITY](/images/research/eb7d0065-7786-4317-8029-2509a7fe4e2f/small/31267.jpg)
research NEW CHALLENGE TO CANCER AND LONGEVITY
A group has developed therapies that show promise for treating cancer and various other conditions.
![Targeting integrin pathways: mechanisms and advances in therapy](/images/research/e990b25e-03a3-4ba7-b9e2-7e002829fe73/small/16752.jpg)
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research 69-Year-Old Man With Dysuria and Right Lower Abdominal Pain
![Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction](/images/research/5959b841-cc8c-48ae-b794-581b9723687a/small/14545.jpg)
research Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction
Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
![Adipose-derived stromal cell in regenerative medicine: A review](/images/research/4649584e-b6ba-4ccf-8353-549a578fdab0/small/16018.jpg)
research Adipose-derived stromal cell in regenerative medicine: A review
Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
![Histogenesis of keratoacanthoma: histochemical and immunohistochemical study](/images/research/6de554ea-421e-43d7-97b0-44a32d80b1c2/small/29179.jpg)
research Histogenesis of keratoacanthoma: histochemical and immunohistochemical study
Keratoacanthoma comes from hair follicle cells.
![Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture](/images/research/4c919cd3-8976-41bb-9205-372c5e6538d9/small/19673.jpg)
research Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture
Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
![The Dynamics of the Skin’s Immune System](/images/research/35062899-7615-4cf0-80b6-ceddd9fbef71/small/19356.jpg)
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
![Choreographing Immunity in the Skin Epithelial Barrier](/images/research/5bbfcc4b-8a66-4a7e-9a98-f5fe38925aed/small/12701.jpg)
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
![Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg–like Cells, and Common EGFR Somatic Mutations](/images/research/f2eef87d-8eb7-4272-84f1-2e624ce4b45a/small/19242.jpg)
research Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg–like Cells, and Common EGFR Somatic Mutations
Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
![Wound Healing: A Cellular Perspective](/images/research/9dde12dd-3934-4b3b-bec6-e0b163969845/small/19385.jpg)
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
![Novel potential therapeutic targets of alopecia areata](/images/research/c2c72535-2074-40e4-b5be-2e332a4ba9e5/small/16669.jpg)
research Novel potential therapeutic targets of alopecia areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
![WNT Signaling in Disease](/images/research/805dbbd4-76c7-44b1-a276-3637d46fe253/small/17630.jpg)
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.