Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study

    Vivian Petersen Wagner, Manoela Domingues Martins, Caroline Siviero Dillenburg … Cristiane H. Squarize
    Studysummary This study found that keratoacanthoma of the lip likely arises from outer root sheath cells, based on the presence of specific keratin markers and periodic acid-Schiff staining patterns.
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    Research cited in this study 9

    1. Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk Nature Communications · 2014
    2. The Changes in the Expression Levels of Follicular Markers in Keratoacanthoma Depend on the Stage: Keratoacanthoma Is a Follicular Neoplasm Exhibiting Infundibular/Isthmic Differentiation Without Expression of CK15 Journal of Cutaneous Pathology · 2014
    3. Keratin Gene Mutations in Disorders of Human Skin and Its Appendages Archives of Biochemistry and Biophysics · 2010
    4. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    5. Human Hair Keratin-Associated Proteins International review of cytology · 2006
    6. Keratins of the Human Hair Follicle International review of cytology · 2005
    7. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989
    8. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986
    9. The Keratoacanthoma: A Review Journal of Surgical Oncology · 1979

    Related research 5

    1. Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study Oral surgery, oral medicine, oral pathology and oral radiology · 2014
    2. Pilomatricoma Can Differentiate Not Only Towards Hair Matrix and Hair Cortex, But Also Follicular Infundibulum, Outer Root Sheath and Hair Bulge Experimental Dermatology · 2009
    3. An Immunohistochemical Study on Cell Differentiation in the Outer Root Sheath of Normal Human Anagen Hair Follicles with Antikeratin Monoclonal Antibodies PubMed · 1990
    4. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    5. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981