Search

for
Search:

GlossaryKeratin 10 (K10)

protein crucial for skin's structural integrity and resilience

Keratin 10 (KRT10) is a type of protein found in the upper layers of the skin, specifically in the epidermis. It plays a crucial role in maintaining the structural integrity and resilience of the skin by forming a network of intermediate filaments that provide mechanical support. Mutations in the KRT10 gene can lead to skin disorders such as epidermolytic hyperkeratosis, which is characterized by blistering and thickening of the skin.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 337 results

research Missense Mutation Y449H of the K10 Gene in a Patient with Severe Epidermolytic Ichthyosis

3 citations, March 2019 in “European Journal of Dermatology”

A specific gene mutation (Y449H in K10) was found in a patient with severe skin disorder.

research Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation

32 citations, April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Loss of keratin K2 causes skin problems and inflammation.

research Loss of Keratin 10 Is Accompanied by Increased Sebocyte Proliferation and Differentiation

36 citations, January 2004 in “European journal of cell biology”

Without keratin 10, there's more growth and development of oil-producing skin cells.

research Development, Structure, and Keratin Expression in C57BL/6J Mouse Eccrine Glands

29 citations, November 2011 in “Veterinary pathology”

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

research Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study

16 citations, October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology”

Keratoacanthoma comes from hair follicle cells.

View more "k10" in research →

Community Join

0 / 0 results

— no results