Lrig1 Expression in Human Sebaceous Gland Tumors

    May 2016 in “ Dermatopathology ”
    Jöri Pünchera, Larry D. Barnes, Gürkan Kaya
    Studysummary The researchers reported that Lrig1 overexpression was observed in 100% of sebaceous carcinoma cases, suggesting it may serve as a potential marker for poorly differentiated sebaceous carcinoma.
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    Research cited in this study 7

    1. C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis Cell reports · 2013
    2. Development and Homeostasis of the Sebaceous Gland Seminars in Cell & Developmental Biology · 2012
    3. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    4. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    5. Obesity Resistance of the Stearoyl-CoA Desaturase-Deficient (Scd1 -/-) Mouse Results from Disruption of the Epidermal Lipid Barrier and Adaptive Thermoregulation Biological Chemistry · 2007
    6. Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice Journal of Investigative Dermatology · 2003
    7. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002