56 citations
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December 2011 in “Steroids” This review discusses the genetics and variable phenotypic expression of nonclassic congenital adrenal hyperplasia, and reports no new clinical results; the authors call for further research on long-term health impacts and treatment strategies.
52 citations
,
August 2021 in “Microorganisms” This review observes higher ACE2 expression in myocardial and lung tissues of heart failure and COPD patients but finds no link between RAAS inhibitors and COVID-19 severity.
1 citations
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November 2023 in “Medicina” This narrative review emphasizes the significant improvements in mental well-being linked to gender-affirming treatments while highlighting the need for ongoing research into hormone therapy's long-term effects and its impact on transgender individuals' reproductive health.
July 2025 in “Journal of Education Health and Sport” This review found that androgenetic alopecia may be associated with increased risks of cardiovascular disease, metabolic disorders, and mental health impacts, suggesting its potential as a biomarker for systemic conditions.
This review explores the risk factors, associated comorbidities, and psychological impacts of early-onset androgenetic alopecia, highlighting its complexity and potential implications for treatment response and overall health.
December 2021 in “Acta Marisiensis” This review discusses the clinical significance, mechanisms, and treatment options of insulin resistance, emphasizing its impact on endocrine diseases and the need for further research into inflammatory cytokines.
August 2008 in “Obstetrics & gynecology science” This review discusses the various features, diagnostic challenges, and associated immediate and long-term morbidities of polycystic ovary syndrome, highlighting its significant impact on quality of life and costs, but reports no new clinical results.
January 2025 in “Applied Sciences” This review examines sulforaphane's interactions with hormone-mediated health conditions, focusing on gender-specific health issues, but reports no new original research findings.
3 citations
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June 2023 in “European heart journal open” This study found that oligo-amenorrhea/menstrual irregularity in women is associated with an increased risk of overall cardiovascular disease, coronary heart disease, and myocardial infarction, while evidence linking hyperandrogenism or polycystic ovaries to cardiovascular disease remains mixed or unexplored.
1 citations
,
October 2025 in “Journal of Personalized Medicine” This review discusses various weight loss treatment options for managing PCOS in women, including lifestyle changes, diet, medications, and surgery, but reports no new clinical results.
1 citations
,
January 2024 This study systematically reviewed recent literature to demonstrate that Long COVID involves complex, multi-systemic symptoms, influenced by factors such as pre-existing conditions and vaccination status, complicating its diagnosis and treatment.
September 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil does not significantly affect blood pressure in patients with hair loss and hypertension.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
1 citations
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January 2015 in “Zdravstvena zastita” This study highlights that workplace stress significantly contributes to various health issues, impacting worker performance and increasing absenteeism.
September 2023 in “JEADV Clinical Practice” This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
January 2022 in “Journal of current research in food science” This review discusses diet and exercise benefits for PCOS, noting that healthier lifestyle choices may help reduce the condition's severity and related complications, but it reports no new clinical results.
59 citations
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October 2020 in “Stem Cell Reviews and Reports” This review discusses potential mechanisms contributing to higher COVID-19 mortality among men, particularly the roles of smoking, genetic factors, and reproductive hormones, without presenting new clinical findings.
28 citations
,
January 1989 in “Toxicologic Pathology” This study found that none of the nine minoxidil-treated autopsy cases showed cardiac pathology attributable to minoxidil, suggesting no direct link between the drug and specific human cardiac lesions.
5 citations
,
March 2024 in “Journal of Clinical Medicine” This study found that one year after recovering from COVID-19, females without comorbidities reported long-COVID symptoms more frequently than males and experienced distinct cardiovascular differences, including lower arterial pressures and higher heart rates, despite fewer ECG abnormalities.
50 citations
,
May 2018 in “International journal of cardiology” This study found associations between genetic predictors of increased testosterone and cardiovascular risk factors, but the implications for testosterone supplementation are unclear due to uncertainties in genetic variant functions.
43 citations
,
September 2021 in “Nutrients” This review discusses the vast potential uses of persimmon beyond its dietary benefits, including applications in sustainability and new product development, but reports no new clinical outcomes.
This review discusses cyclosporine A's mechanisms of action and side effects compared to tacrolimus in renal transplantation, but it reports no new experimental results; the authors highlight implications for cardiovascular risk management.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that collagen peptides consistently provide modest improvements in skin hydration and elasticity and varying benefits for body composition and cardiometabolic markers, although effects on blood sugar control are less consistent; variations in source, dose, and study definitions limit generalizability.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that collagen peptides provide consistent, modest benefits for skin hydration and elasticity, with variable effects on body composition and cardiometabolic risk markers, though some outcomes remain inconsistent due to trial heterogeneity.
January 2025 in “i-manager s Journal on Life Sciences” This review discusses PCOD's pathophysiology, clinical features, and management strategies but reports no new clinical findings, emphasizing the need for early diagnosis and multidisciplinary management.
5 citations
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December 2021 in “Scientific Reports” In this study, researchers found that in mice, gonadal hormones and biological sex do not affect the expression of SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in the respiratory tract, regardless of disease state.
7 citations
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January 2019 in “Headache” This source suggests that migraine prevalence increases in transgender women using oestrogen and decreases in transgender men using testosterone, with high oral oestrogen doses in transgender women potentially linked to aura risk.
3 citations
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March 2023 in “Life” This review discusses recent findings on wound healing with a focus on adipose tissue biology and obesity, but presents no new clinical results.
166 citations
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October 2018 in “Endocrine Reviews” This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.
June 2021 in “Health and Society” In this study, lifestyle changes, particularly weight loss, were reported to improve symptoms and prognosis of Polycystic Ovary Syndrome, especially in patients who are overweight or obese.