2 citations
,
October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics” Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
1 citations
,
February 2014 in “Analytical Letters” This study developed a fast and sensitive ultra-high performance liquid chromatography method to quantify ketoconazole in antidandruff emulsions, showing comparable results to labeled concentrations.
April 2016 in “Annals of laboratory medicine” The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.
1 citations
,
April 2015 in “Drug research” This study concluded that two different pharmaceutical formulations of finasteride were bioequivalent in terms of rate and extent of absorption based on pharmacokinetic evaluations in a randomized crossover study with 38 volunteers.
49 citations
,
December 2017 in “Journal of pharmaceutical and biomedical analysis” This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.
3 citations
,
February 2021 in “Molecules” In this study, researchers developed a sensitive assay to measure the inhibition of steroid 5-α reductase (5AR) by chemicals like finasteride and dutasteride, revealing species-specific differences in inhibitor efficacy between human and fish cell lines.
71 citations
,
January 2014 in “Journal of Proteome Research” In this study, distinct metabolic profiles were identified in women with PCOS, suggesting potential biomarkers for diagnosis based on changes in lipid and androgen metabolism.
11 citations
,
November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications” This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.
48 citations
,
January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
7 citations
,
June 2017 in “Omics” This study developed a new proteomic method to identify and assess ancient hair proteins using only small amounts of sample, providing insights into hair protein alteration processes over time.
7 citations
,
December 2014 in “Gynecological Endocrinology” This study found that LC-MS/MS is a more reliable method than immunoassays for measuring serum 17OHP and androgen levels in women with hyperandrogenism.
21 citations
,
November 2010 in “Talanta” This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.
467 citations
,
October 2014 in “European Journal of Endocrinology” This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.
76 citations
,
February 2015 in “Industrial Crops and Products” This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.
4 citations
,
May 2021 in “Molecules” This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.
1 citations
,
October 2017 in “Food Additives & Contaminants: Part A” This study identified a new minoxidil analogue called triaminodil in an illegal hair-growth supplement, but no data on its chemical, toxicological, or pharmacological properties are available yet.
January 2019 in “Analytical Science and Technology” This study developed a rapid method using advanced chromatography and mass spectrometry to detect hair-growth enhancing compounds, discovering synthetic drugs in about 21% of tested supplements.
January 2024 in “Institutional Repositories DataBase (IRDB)” This study developed a method to measure local steroid hormone concentrations in hair, providing new insights into hormone dynamics associated with androgenetic alopecia.
3 citations
,
January 2009 in “Eclética Química” This study proposed a simple, rapid permanganometric method for determining minoxidil concentrations in pharmaceutical samples, offering comparable accuracy to chromatographic methods with recovery rates of 94.5 to 95.2%.
4 citations
,
January 2018 in “Forensic Science International” This study reported that a newly developed UHPLC-MS/MS method detected illegal synthetic hair-growth compounds in 10% of 76 hair-growth products, highlighting the need for ongoing monitoring to protect public health.
7 citations
,
April 2022 in “Journal of pharmaceutical and biomedical analysis” This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.
5 citations
,
April 2024 in “ACS Chemical Neuroscience” This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.
3 citations
,
November 2022 in “Separations” This study successfully established and validated a method using LC-MS/MS to measure multiple androgens in plasma, finding that individuals with acne had higher levels of certain androgens compared to those with obesity.
1 citations
,
March 2012 in “Acta Pharmaceutica Sinica B” This study developed methods for detecting carboxy-finasteride in urine for doping control, demonstrating detection up to 49 hours post-administration with high precision and accuracy.
January 2023 in “Brazilian Journal of Pharmaceutical Sciences” This study concluded that the liquid chromatography-mass spectrometry method developed is viable for accurately quantifying spironolactone and its metabolite canrenone in plasma despite interference from plasma components.
2 citations
,
March 2014 in “European Journal of Chemistry” This study developed and validated a liquid chromatography-mass spectrometry method for accurately identifying and quantifying tamsulosin and finasteride in pharmaceutical forms, showing its effectiveness for quality control.
22 citations
,
January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study developed and validated a mass spectrometric method to measure hydroxy-androgens in serum, which aids in understanding androgen synthesis in castration resistant prostate cancer.
February 2024 in “ACS Omega” This study found that the topical Shen Bai hair growing decoction may improve androgenetic alopecia in mice by suppressing TNF-α and IL-6 levels, enhancing follicle density, and reducing apoptosis.
April 2025 in “Advances in Traditional Medicine” In this study, a film-forming spray with rosemary essential oil increased hair density in volunteers over 16 weeks, suggesting it has potential efficacy for treating androgenetic alopecia by enhancing hair density restoration.
April 2025 in “Cosmetics” This study found that Clinopodium bolivianum essential oil, particularly in combing cream, demonstrated notable antioxidant activity, with potential applications as a natural antioxidant in cosmetic formulations.