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    GlossaryC3H/HeJ mouse

    strain with impaired immune response due to TLR4 mutation

    The C3H/HeJ mouse is a specific strain of laboratory mouse that is commonly used in scientific research. This strain is notable for its susceptibility to bacterial infections due to a mutation in the TLR4 gene, which impairs its immune response. Researchers often use C3H/HeJ mice to study immune system function, infectious diseases, and related biological processes.

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